RAI14 Gene Summary [Human]
Predicted to enable actin binding activity. Predicted to be involved in several processes, including apoptotic signaling pathway; regulation of NIK/NF-kappaB signaling; and spermatogenesis. Located in cytosol; fibrillar center; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | RAI14 |
| Official Name | retinoic acid induced 14 [Source:HGNC Symbol;Acc:HGNC:14873] |
| Ensembl ID | ENSG00000039560 |
| Bio databases IDs | |
| Aliases | retinoic acid induced 14, novel retinal pigment epithelial |
| Synonyms | 1700008J19Rik, 1700020L11Rik, Ankycorbin, mKIAA1334, NORPEG, RAI13, retinoic acid induced 14 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RAI14 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- transcription regulator
- Ankyrin repeats (many copies)
- Weak chloroplast movement under blue light
- Ankyrin repeats (3 copies)
- protein binding
- Calcium binding and coiled-coil domain (CALCOCO1) like
- Septation ring formation regulator, EzrA
- Ankyrin repeat
- ankyrin repeats
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- gout
role in cell
- expression in
- phosphorylation in
- number
- proliferation
- apoptosis
- synthesis in
- migration
- upregulation in
- G1 phase
- invasion by
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- fibrillar center
- Cytoplasm
- cilia
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human RAI14 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- spermatogenesis
- cell differentiation
Cellular Component
Where in the cell the gene product is active
- anchoring junction
- cell cortex
- stress fiber
- cytosol
- fibrillar center
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding