UQCRQ Gene Summary [Human]
This gene encodes a ubiquinone-binding protein of low molecular mass. This protein is a small core-associated protein and a subunit of ubiquinol-cytochrome c reductase complex III, which is part of the mitochondrial respiratory chain. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | UQCRQ |
| Official Name | ubiquinol-cytochrome c reductase complex III subunit VII [Source:HGNC Symbol;Acc:HGNC:29594] |
| Ensembl ID | ENSG00000164405 |
| Bio databases IDs | |
| Aliases | ubiquinol-cytochrome c reductase complex III subunit VII, ubiquinol-cytochrome c reductase, complex III subunit VII, complex III subunit 8 |
| Synonyms | 1100001F06Rik, 1500040F11Rik, 5830407L17Rik, 9.5kDa, c1502, LOW MOLECULAR MASS UBIQUINONE binding, MC3DN4, QCR8, QP-C, ubiquinol-cytochrome c reductase complex III subunit VII, ubiquinol-cytochrome c reductase, complex III subunit VII, UQCR7, Uqcrb |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human UQCRQ often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- UcrQ family
- enzyme
- protein binding
Pathways
Biological processes and signaling networks where the UQCRQ gene in human plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- pH resistant lipid raft fraction
- detergent resistant lipid raft fraction
- Mitochondria
- mitochondrial inner membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human UQCRQ gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cerebellar Purkinje cell layer development
- midbrain development
- pons development
- subthalamus development
- hippocampus development
- cellular respiration
- hypothalamus development
- mitochondrial electron transport, ubiquinol to cytochrome c
- thalamus development
- pyramidal neuron development
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- mitochondrial respiratory chain complex III
- mitochondrial inner membrane