Mef2d

Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; histone deacetylase binding activity; and protein dimerization activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including osteoblast differentiation; skeletal muscle cell differentiation; and skeletal system development. Located in cytoplasm and nucleus. Is expressed in several structures, including brain; early conceptus; embryo mesenchyme; female reproductive system; and urinary system. Orthologous to human MEF2D (myocyte enhancer factor 2D). [provided by Alliance of Genome Resources, Apr 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mef2d often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Mef2d gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Mef2d gene, providing context for its role in the cell.