Ssr4 Gene Summary [Mouse]
Predicted to be located in endoplasmic reticulum. Predicted to be part of Sec61 translocon complex. Predicted to be active in endomembrane system. Is expressed in several structures, including gut; jaw; musculoskeletal system; nasal capsule; and submandibular gland primordium. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Iy. Orthologous to human SSR4 (signal sequence receptor subunit 4). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ssr4 |
| Official Name | signal sequence receptor, delta [Source:MGI Symbol;Acc:MGI:1099464] |
| Ensembl ID | ENSMUSG00000002014 |
| Bio databases IDs | |
| Aliases | signal sequence receptor, delta |
| Synonyms | CDG1Y, SIGNAL SEQUENCE receptor delta, signal sequence receptor, delta, signal sequence receptor subunit 4, SIGNAL SEQUENCE receptor δ, signal sequence receptor, δ, SSR-delta, SSR-δ, translocon-associated protein delta, translocon-associated protein δ, Trap, TRAPD, TRAP-delta, TRAP-δ |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ssr4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Translocon-associated protein, delta subunit precursor (TRAP-delta)
Pathways
Biological processes and signaling networks where the Ssr4 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Endoplasmic Reticulum
- endoplasmic reticulum membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ssr4 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome
- endomembrane system
- endoplasmic reticulum
- Sec61 translocon complex