Ssbp2 Gene Summary [Mouse]
Predicted to enable single-stranded DNA binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Is expressed in several structures, including adipose tissue; alimentary system; central nervous system; genitourinary system; and limb. Orthologous to human SSBP2 (single stranded DNA binding protein 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Processed Transcript |
| Official Symbol | Ssbp2 |
| Official Name | single-stranded DNA binding protein 2 [Source:MGI Symbol;Acc:MGI:1914220] |
| Ensembl ID | ENSMUSG00000003992 |
| Bio databases IDs | |
| Aliases | single-stranded DNA binding protein 2 |
| Synonyms | 1500004K09Rik, 2310079I02Rik, 9330163K02Rik, A830008M03RIK, HSPC116, RGD1562968, single-stranded DNA binding protein 2, SOSS-B2, SSDP2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ssbp2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- transcription regulator
- protein binding
- Single-stranded DNA binding protein, SSDP
- LisH
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- anemia
- adenoma formation
- epithelial neoplasia
- benign neoplasia
- epithelial cancer
- cancer
- glioblastoma
- glioblastoma cancer
- bipolar disorder
- lung adenocarcinoma formation
role in cell
- expression in
- differentiation
- cell cycle progression
- number
- turnover in
- clonogenicity
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nuclear fraction
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ssbp2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of transcription, DNA-dependent
- positive regulation of transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- single-stranded DNA binding