Arpp19 Gene Summary [Mouse]
Predicted to enable several functions, including potassium channel regulator activity; protein phosphatase 2A binding activity; and protein phosphatase inhibitor activity. Predicted to be involved in G2/M transition of mitotic cell cycle and positive regulation of gluconeogenesis. Predicted to be active in cytoplasm. Is expressed in secondary oocyte. Orthologous to human ARPP19 (cAMP regulated phosphoprotein 19). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Arpp19 |
| Official Name | cAMP-regulated phosphoprotein 19 [Source:MGI Symbol;Acc:MGI:1891691] |
| Ensembl ID | ENSMUSG00000007656 |
| Bio databases IDs | |
| Aliases | cAMP-regulated phosphoprotein 19 |
| Synonyms | 2700024H10Rik, Arpp12, ARPP-16, cAMP-regulated phosphoprotein 19, Cyclic AMP phosphoprotein, 19 kD, ENSAL |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Arpp19 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein phosphatase inhibitor activity
- phosphatase inhibitor
- cAMP-regulated phosphoprotein/endosulfine conserved region
- protein phosphatase binding
- potassium channel regulator
- protein phosphatase regulator
- protein binding
- receptor binding
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- cytosol
- nucleoplasm
- synapse
- dendrites
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Arpp19 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell division
- G2/M transition of mitotic cell cycle
- positive regulation of glucose import
- negative regulation of protein dephosphorylation
- positive regulation of gluconeogenesis
- mitotic cell cycle
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein phosphatase inhibitor activity
- protein binding
- phosphatase inhibitor activity
- receptor binding
- potassium channel regulator activity
- protein phosphatase 2A binding
- protein phosphatase regulator activity