Rabl6 Gene Summary [Mouse]
Predicted to enable GTP binding activity. Predicted to be located in centrosome and cytoplasm. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including adipose tissue; alimentary system; genitourinary system; hemolymphoid system gland; and nervous system. Orthologous to human RABL6 (RAB, member RAS oncogene family like 6). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rabl6 |
| Official Name | RAB, member RAS oncogene family-like 6 [Source:MGI Symbol;Acc:MGI:2442633] |
| Ensembl ID | ENSMUSG00000015087 |
| Bio databases IDs | |
| Aliases | RAB, member RAS oncogene family-like 6 |
| Synonyms | B230208H17Rik, C9orf86, FLJ10101, PARF, pp8875, RAB, member RAS oncogene family-like 6, RBEL1, Rbel1a, Rbel1b, RGD1307615 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rabl6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- GTP binding
- Small GTPase of the Ras superfamily (ill-defined subfamily)
- Ras family
- Rab subfamily of small GTPases
- protein binding
- Ras of Complex, Roc, domain of DAPkinase
- P-loop containing Nucleoside Triphosphate Hydrolases
- Ras subfamily of RAS small GTPases
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- ovarian carcinoma
- epithelial ovarian cancer
- breast adenocarcinoma
- epithelial uterine cancer
- gastric carcinoma
- gastric epithelial cancer
- colon carcinoma
- colon epithelial cancer
- autosomal recessive nonsyndromic mental retardation
role in cell
- apoptosis
- proliferation
- phosphorylation in
- expression in
- growth
- cell death
- ubiquitination in
- G1 phase
- polyubiquitination in
- stabilization in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- basal bodies
- centrosome
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rabl6 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- nucleus
- centrosome
- cytoplasm
- cytosol
Molecular Function
What the gene product does at the molecular level
- GTP binding
- protein binding