Txndc17 Gene Summary [Mouse]
Predicted to enable peroxidase activity and protein-disulfide reductase [NAD(P)H] activity. Predicted to be involved in tumor necrosis factor-mediated signaling pathway. Predicted to be active in cytosol. Orthologous to human TXNDC17 (thioredoxin domain containing 17). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Txndc17 |
| Official Name | thioredoxin domain containing 17 [Source:MGI Symbol;Acc:MGI:1289248] |
| Ensembl ID | ENSMUSG00000020803 |
| Bio databases IDs | |
| Aliases | thioredoxin domain containing 17 |
| Synonyms | 4831443O22Rik, D11Ertd672e, thioredoxin domain containing 17, TRP14, TXNL5 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Txndc17 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- peroxidase
- Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold
- enzyme
- protein binding
- protein-disulfide reductase
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- chronic obstructive pulmonary disease
- obesity
- ceruletide-induced acute pancreatitis
role in cell
- cohesion
- cohesion in
- reduction in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Txndc17 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- tumor necrosis factor-mediated signaling pathway
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome
- cytosol
Molecular Function
What the gene product does at the molecular level
- peroxidase activity
- protein binding
- protein-disulfide reductase activity