Septin3 Gene Summary [Mouse]
Predicted to enable several functions, including GTP binding activity; GTPase activity; and identical protein binding activity. Involved in protein catabolic process at presynapse. Part of septin complex. Is active in presynapse. Is expressed in several structures, including central nervous system; peripheral nervous system ganglion; sensory organ; somite; and testis. Orthologous to human SEPTIN3 (septin 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Septin3 |
| Official Name | septin 3 [Source:MGI Symbol;Acc:MGI:1345148] |
| Ensembl ID | ENSMUSG00000022456 |
| Bio databases IDs | |
| Aliases | septin 3 |
| Synonyms | 3110018K01RIK, B530002E20Rik, bK250D10.3, Gm46500, LOC105373094, SEP3, SEPT3 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Septin3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- GTP binding
- 50S ribosome-binding GTPase
- enzyme
- protein binding
- identical protein binding
- Septin
- P-loop containing Nucleoside Triphosphate Hydrolases
Pathways
Biological processes and signaling networks where the Septin3 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- peripheral membrane fraction
- cytoskeleton
- presynaptic regions
- presynaptic membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Septin3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein localization
Cellular Component
Where in the cell the gene product is active
- microtubule cytoskeleton
- cell division site
- septin complex
- septin ring
Molecular Function
What the gene product does at the molecular level
- GTP binding
- identical protein binding
- protein binding
- GTPase activity
- binding, bridging