Cat

Enables aminoacylase activity and catalase activity. Acts upstream of or within several processes, including hydrogen peroxide catabolic process; positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction; and regulation of DNA-binding transcription factor activity. Located in peroxisomal membrane. Is expressed in several structures, including alimentary system; early conceptus; heart; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in several diseases, including acatalasia; eye disease (multiple); lung disease (multiple); osteonecrosis; and pseudoxanthoma elasticum. Orthologous to human CAT (catalase). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cat often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Cat gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Cat gene, providing context for its role in the cell.