Ccng2 Gene Summary [Mouse]
Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Acts upstream of or within regulation of cell cycle. Predicted to be located in cytosol. Predicted to be part of cyclin-dependent protein kinase holoenzyme complex. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including cerebral cortex; lung; and tibialis anterior. Orthologous to human CCNG2 (cyclin G2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ccng2 |
| Official Name | cyclin G2 [Source:MGI Symbol;Acc:MGI:1095734] |
| Ensembl ID | ENSMUSG00000029385 |
| Bio databases IDs | |
| Aliases | cyclin G2 |
| Synonyms | CYCLIN G2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ccng2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- cyclin box
- Cyclin box fold superfamily
- Cyclin, N-terminal domain
- domain present in cyclins, TFIIB and Retinoblastoma
Pathways
Biological processes and signaling networks where the Ccng2 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- idiopathic scoliosis
- amyotrophic lateral sclerosis
- sarcoidosis
- mature B-cell neoplasia
- plasma cell neoplasm
- B cell cancer
role in cell
- S phase
- mineralization
- proliferation
- survival
- cell cycle progression
- formation
- G1 phase
- colony formation
- G2 phase
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- perinuclear region
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ccng2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell division
- regulation of cell cycle
- regulation of cyclin-dependent protein kinase activity
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- cyclin-dependent protein kinase holoenzyme complex
Molecular Function
What the gene product does at the molecular level
- cyclin-dependent protein kinase regulator activity