Nup210 Gene Summary [Mouse]
Predicted to be involved in protein-containing complex assembly. Located in nuclear envelope. Is expressed in several structures, including alimentary system; brain; lung; metanephros; and skin. Orthologous to human NUP210 (nucleoporin 210). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Nup210 |
| Official Name | nucleoporin 210 [Source:MGI Symbol;Acc:MGI:1859555] |
| Ensembl ID | ENSMUSG00000030091 |
| Bio databases IDs | |
| Aliases | nucleoporin 210 |
| Synonyms | 9830001L10, Gp120, gp190, GP210, nucleoporin 210, POM210 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Nup210 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Bacterial Ig-like domain (group 2)
- protein binding
- Bacterial Ig-like domain 2
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- epithelial cancer
- non-insulin-dependent diabetes mellitus
- metastasis
- COVID-19
- coronary artery disease
- liver cancer
- hepatocellular carcinoma
- neonatal late-onset sepsis
role in cell
- expression in
- differentiation
- activation in
- proliferation
- cell viability
- function
- area
- number
- abnormal morphology
- activation
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- interchromatin granule cluster fractions
- nuclear pores
- inner nuclear membrane
- nuclear rim
- nuclear envelope
- detergent-soluble fraction
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Nup210 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nucleocytoplasmic transport
- protein transport
- mRNA transport
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- nuclear envelope
- nuclear membrane
- membrane
- nuclear pore
Molecular Function
What the gene product does at the molecular level
- protein binding