Sec13 Gene Summary [Mouse]
Predicted to enable identical protein binding activity and structural molecule activity. Involved in protein exit from endoplasmic reticulum. Predicted to be located in endoplasmic reticulum; lysosomal membrane; and nucleus. Predicted to be part of COPII vesicle coat; GATOR2 complex; and nuclear pore outer ring. Predicted to colocalize with kinetochore. Is expressed in cranium; mandible; and maxilla. Orthologous to human SEC13 (SEC13 homolog, nuclear pore and COPII coat complex component). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Sec13 |
| Official Name | SEC13 homolog, nuclear pore and COPII coat complex component [Source:MGI Symbol;Acc:MGI:99832] |
| Ensembl ID | ENSMUSG00000030298 |
| Bio databases IDs | |
| Aliases | SEC13 homolog, nuclear pore and COPII coat complex component |
| Synonyms | 1110003H02Rik, AC022384.1, D3S1231E, npp-20, SEC13 homolog, nuclear pore and COPII coat complex component, SEC13L1, Sec13p, SEC13R |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Sec13 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- WD40 repeats
- WD domain, G-beta repeat
- WD40
- protein binding
- identical protein binding
- transporter
Pathways
Biological processes and signaling networks where the Sec13 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- interchromatin granule cluster fractions
- detergent-insoluble fractions
- endoplasmic reticulum mitochondria contact site
- intracellular membrane-bounded organelle
- intranuclear region
- perinuclear region
- cellular membrane
- vesicles
- Endoplasmic Reticulum
- cytosol
- endoplasmic reticulum membrane
- endoplasmic reticulum exit sites
- Golgi membrane
- Golgi buds
- lysosome membrane
- nuclear pores
- inner nuclear membrane
- nucleoplasm
- nuclear rim
- nuclear envelope
- cytoplasmic vesicles
- kinetochores
- detergent-soluble fraction
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Sec13 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nucleocytoplasmic transport
- protein exit from endoplasmic reticulum
- cellular response to nutrient levels
- COPII-coated vesicle budding
- protein import into nucleus
- cargo loading into COPII-coated vesicle
- intracellular protein transport
- positive regulation of TOR signaling cascade
- mRNA transport
Cellular Component
Where in the cell the gene product is active
- Nup107-160 complex
- kinetochore
- lysosomal membrane
- nucleoplasm
- nuclear pore
- endoplasmic reticulum membrane
- nuclear envelope
- extracellular vesicular exosome
- intracellular membrane-bounded organelle
- ER to Golgi transport vesicle membrane
- cytosol
- COPII vesicle coat
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding
- structural molecule activity