Pik3r4

Predicted to enable protein serine/threonine kinase activity. Involved in cellular response to glucose starvation. Located in axoneme. Part of phosphatidylinositol 3-kinase complex, class III. Is expressed in central nervous system; embryo; retina inner nuclear layer; retina nuclear layer; and retina outer nuclear layer. Orthologous to human PIK3R4 (phosphoinositide-3-kinase regulatory subunit 4). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Pik3r4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Pik3r4 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Pik3r4 gene, providing context for its role in the cell.