Dusp10

Enables MAP kinase phosphatase activity. Involved in several processes, including negative regulation of ERK1 and ERK2 cascade; negative regulation of epithelial cell migration; and negative regulation of epithelium regeneration. Acts upstream of or within several processes, including negative regulation of protein kinase activity; negative regulation of respiratory burst involved in inflammatory response; and negative regulation of stress-activated MAPK cascade. Predicted to be located in nucleoplasm. Predicted to be active in cytosol. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human DUSP10 (dual specificity phosphatase 10). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Dusp10 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Dusp10 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Dusp10 gene, providing context for its role in the cell.