Lin9 Gene Summary [Mouse]
Predicted to enable DNA binding activity. Predicted to be involved in regulation of cell cycle and regulation of transcription by RNA polymerase II. Predicted to be part of transcription repressor complex. Predicted to be active in nucleoplasm. Is expressed in telencephalon ventricular layer. Orthologous to human LIN9 (lin-9 DREAM MuvB core complex component). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Lin9 |
| Official Name | lin-9 homolog (C. elegans) [Source:MGI Symbol;Acc:MGI:1919818] |
| Ensembl ID | ENSMUSG00000058729 |
| Bio databases IDs | |
| Aliases | lin-9 homolog (C. elegans) |
| Synonyms | 2700022J23Rik, BARA, BARPsv, lin-9 DREAM MuvB core complex component, LOC360888, LOC690072, mLin-9, TGS, TGS1, TGS2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Lin9 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- LIN9 C-terminal
- protein binding
- DIRP
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- hypoplasia
- weight gain
- insulin-dependent diabetes mellitus
role in cell
- proliferation
- expression in
- growth
- cell cycle progression
- morphology
- transcription in
- transformation
- G2/M phase transition
- senescence
- checkpoint recovery in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nuclear fraction
- nucleoplasm
- chromatin
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Lin9 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- transcription, DNA-dependent
- DNA biosynthetic process
- reproductive process
- regulation of cell cycle
- regulation of transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- transcriptional repressor complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- DNA binding
- protein binding