Baiap2

Enables PDZ domain binding activity; scaffold protein binding activity; and transcription coregulator binding activity. Involved in several processes, including cellular response to L-glutamate; cellular response to epidermal growth factor stimulus; and regulation of synapse organization. Located in several cellular components, including dendrite; lamellipodium; and neuron projection branch point. Is active in several cellular components, including postsynaptic cytosol; postsynaptic density, intracellular component; and presynaptic cytosol. Human ortholog(s) of this gene implicated in Gilles de la Tourette syndrome; attention deficit hyperactivity disorder; and autism spectrum disorder. Orthologous to human BAIAP2 (BAR/IMD domain containing adaptor protein 2). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Baiap2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Baiap2 gene in rat plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the rat Baiap2 gene, providing context for its role in the cell.