Il17re Gene Summary [Rat]

Predicted to enable interleukin-17 receptor activity. Predicted to be involved in cytokine-mediated signaling pathway and inflammatory response. Predicted to be located in plasma membrane. Orthologous to human IL17RE (interleukin 17 receptor E). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Il17re
Official Name
interleukin 17 receptor E [Source:RGD Symbol;Acc:735148]
Ensembl ID
ENSRNOG00000009204
Bio databases IDs NCBI: 362417 Ensembl: ENSRNOG00000009204
Aliases interleukin 17 receptor E
Synonyms Il25r, interleukin 17 receptor E
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Il17re often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • SEFIR domain
  • protein binding
  • Interleukin-17 receptor extracellular region

Pathways

Biological processes and signaling networks where the Il17re gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • systemic lupus erythematosus
  • psoriasis
  • liver damage
  • corneal neovascularization
  • infection by bacteria
regulates
  • pro-inflammatory cytokine
role in cell
  • recruitment

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Il17re gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • inflammatory response
  • cytokine-mediated signaling pathway

Cellular Component

Where in the cell the gene product is active
  • cytoplasm
  • extracellular region
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • interleukin-17 receptor activity

Gene-Specific Assays for Results You Can Trust

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