Il17c Gene Summary [Rat]
Predicted to enable cytokine activity. Predicted to be involved in inflammatory response and signal transduction. Predicted to act upstream of or within neutrophil differentiation and positive regulation of cytokine production involved in inflammatory response. Predicted to be located in extracellular space. Orthologous to human IL17C (interleukin 17C). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Il17c |
| Official Name | interleukin 17C [Source:RGD Symbol;Acc:1582798] |
| Ensembl ID | ENSRNOG00000013007 |
| Bio databases IDs | |
| Aliases | interleukin 17C |
| Synonyms | CX2, interleukin 17C, LOC687591 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Il17c often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Interleukin-17
- cytokine
Pathways
Biological processes and signaling networks where the Il17c gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- colorectal cancer
- colorectal neoplasia
- gastrointestinal neoplasia
- hyperplasia
- psoriasis
- experimental autoimmune encephalomyelitis
- peroxisomal acyl CoA oxidase deficiency
- colon neoplasm
- experimental hepatitis
- small intestine neoplasm
role in cell
- proliferation
- expression in
- production in
- number
- differentiation
- cellular infiltration by
- survival
- immune response
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Il17c gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- inflammatory response
- cell-cell signaling
- cell surface receptor signaling pathway
Cellular Component
Where in the cell the gene product is active
- extracellular space
- extracellular region
Molecular Function
What the gene product does at the molecular level
- cytokine activity