F13b Gene Summary [Rat]
Predicted to be involved in blood coagulation, fibrin clot formation. Orthologous to human F13B (coagulation factor XIII B chain). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | F13b |
| Official Name | coagulation factor XIII B chain [Source:RGD Symbol;Acc:1311668] |
| Ensembl ID | ENSRNOG00000012613 |
| Bio databases IDs | |
| Aliases | coagulation factor XIII B chain |
| Synonyms | Cf-13b, coagulation factor XIII B chain, coagulation factor XIII, beta subunit, coagulation factor XIII, β subunit, FXIIIB |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat F13b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- CCP
- protein-glutamine gamma-glutamyltransferase
- enzyme
- protein binding
- Sushi repeat (SCR repeat)
- SUSHI repeat
Pathways
Biological processes and signaling networks where the F13b gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- deficiency of factor XIII subunit B
- susceptibility to venous thrombosis
- impotence
- coagulation factor deficiency syndrome
- congenital factor XIII deficiency
- severe COVID-19
role in cell
- expression in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- perinuclear region
- Golgi Apparatus
- plasma
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat F13b gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- blood coagulation, fibrin clot formation
- blood coagulation
Cellular Component
Where in the cell the gene product is active
- extracellular space
- extracellular region