Ppp1r14a Gene Summary [Rat]
Predicted to enable protein serine/threonine phosphatase inhibitor activity. Predicted to act upstream of or within cellular response to xenobiotic stimulus. Predicted to be located in cytoplasm. Orthologous to human PPP1R14A (protein phosphatase 1 regulatory inhibitor subunit 14A). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ppp1r14a |
| Official Name | protein phosphatase 1, regulatory (inhibitor) subunit 14A [Source:RGD Symbol;Acc:620536] |
| Ensembl ID | ENSRNOG00000020676 |
| Bio databases IDs | |
| Aliases | protein phosphatase 1, regulatory (inhibitor) subunit 14A |
| Synonyms | 1110001M11Rik, CPI-17, PPP1INL, protein phosphatase 1 regulatory inhibitor subunit 14A, protein phosphatase 1, regulatory (inhibitor) subunit 14A, protein phosphatase 1, regulatory inhibitor subunit 14A |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ppp1r14a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- PKC-activated protein phosphatase-1 inhibitor
- protein phosphatase inhibitor activity
- phosphatase
Pathways
Biological processes and signaling networks where the Ppp1r14a gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- prostate cancer
- preeclampsia
- epithelial cancer
- prostatic carcinoma
- androgenic alopecia
- diverticular disease
regulates
- MLCP
- MLC
- MLC PHOSPHATASE
- PPP1CA
role in cell
- long term synaptic depression
- response by
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Ppp1r14a gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of phosphorylation
Cellular Component
Where in the cell the gene product is active
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein serine/threonine phosphatase inhibitor activity