Ppp1r12a

Enables phosphoprotein phosphatase activity. Predicted to be involved in several processes, including centrosome cycle; positive regulation of transcription by RNA polymerase II; and protein dephosphorylation. Predicted to act upstream of or within cellular response to xenobiotic stimulus and regulation of nucleocytoplasmic transport. Predicted to be located in several cellular components, including contractile muscle fiber; cytoskeleton; and kinetochore. Predicted to be part of PTW/PP1 phosphatase complex. Predicted to be active in A band and Z disc. Orthologous to human PPP1R12A (protein phosphatase 1 regulatory subunit 12A). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ppp1r12a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Ppp1r12a gene in rat plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the rat Ppp1r12a gene, providing context for its role in the cell.