General Signal Transduction
Signal transduction transmits and amplifies signals of stimuli from extracellular sources to the nucleus. Signaling molecules include various hormones, growth factors, metabolites, cytokines, chemokines, neurotransmitters, extracellular matrix components, receptors, protein kinases, protein phosphatases, and DNA-binding proteins. The purpose of signal transduction is to regulate the cellular response to the molecular stimuli via changes in gene and protein expression.
Cell Junction and Cytoskeleton-related signaling
Growth Factor Signaling
Angiopoietin Signaling BMP signaling pathway EGF Signaling Ephrin A Signaling Ephrin B Signaling Ephrin Receptor Signaling ErbB Signaling ErbB2-ErbB3 Signaling ErbB4 Signaling FGF Signaling GDNF Family Ligand-Receptor Interactions HGF Signaling IGF-1 Signaling Neuregulin Signaling NGF Signaling PDGF Signaling TGF-β Signaling VEGF Family Ligand-Receptor Interactions VEGF Signaling Wnt/Ca+ pathway WNT/β-catenin Signaling
JAK-STAT signaling
Lipid-based signaling
MAPK signaling
Nucleotide-based signaling
AMPK Signaling cAMP-mediated signaling G Beta Gamma Signaling G Protein Signaling Mediated by Tubby G-Protein Coupled Receptor Signaling GPCR-Mediated Integration of Enteroendocrine Signaling Exemplified by an L Cell GPCR-Mediated Nutrient Sensing in Enteroendocrine Cells Gα12/13 Signaling Gαi Signaling Gαq Signaling Gαs Signaling Protein Kinase A Signaling Rac Signaling RhoA Signaling RhoGDI Signaling Signaling by Rho Family GTPases Thrombin Signaling