TBCB Gene Summary [Human]
Predicted to be involved in cell differentiation and nervous system development. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Processed Transcript |
| Official Symbol | TBCB |
| Official Name | tubulin folding cofactor B [Source:HGNC Symbol;Acc:HGNC:1989] |
| Ensembl ID | ENSG00000105254 |
| Bio databases IDs | |
| Aliases | tubulin folding cofactor B |
| Synonyms | 2410007D12Rik, CG22, CKAP1, Ckap1 predicted, CKAPI, LOC100911774, LOC103690005, TCoB, TUBULIN FOLDING COFACTOR B, ZH14 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TBCB often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Ubl1_cv_Nsp3_N-like
- CAP-Gly domain
- protein binding
- CAP_GLY
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- microtubule cytoskeleton
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TBCB gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- tubulin complex assembly
- nervous system development
- cell differentiation
- post-chaperonin tubulin folding pathway
- cytoplasmic microtubule organization
Cellular Component
Where in the cell the gene product is active
- nucleus
- microtubule cytoskeleton
- microtubule plus end
- cytoplasm
- cell cortex
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding
- microtubule plus-end binding
- alpha-tubulin binding