ELMOD2 Gene Summary [Human]
This gene encodes one of six engulfment and motility (ELMO) domain-containing proteins. This gene is thought to play a role in antiviral responses. Mutations in this gene may be involved in the cause of familial idiopathic pulmonary fibrosis. [provided by RefSeq, Sep 2010]
Details
| Type | Protein Coding |
| Official Symbol | ELMOD2 |
| Official Name | ELMO domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28111] |
| Ensembl ID | ENSG00000179387 |
| Bio databases IDs | |
| Aliases | ELMO domain containing 2 |
| Synonyms | 9830169G11Rik, ELMO/CED-12 domain containing 2, ELMO domain containing 2, LOC686276, RGD1307344 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ELMOD2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- ELMO/CED-12 family
- GTPase activator
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
role in cell
- accumulation in
- fragmentation
- fragmentation in
- morphology
- cohesion
- number
- ciliogenesis in
- multiciliation in
- cohesion in
- multinucleation in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ELMOD2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- defense response to virus
- regulation of defense response to virus
Cellular Component
Where in the cell the gene product is active
- membrane
Molecular Function
What the gene product does at the molecular level
- GTPase activator activity