Kcnq2

Enables calmodulin binding activity; potassium channel activity; and voltage-gated monoatomic ion channel activity. Acts upstream of or within several processes, including chemical synaptic transmission; learning or memory; and nervous system development. Located in cell surface; main axon; and plasma membrane. Part of voltage-gated potassium channel complex. Is expressed in several structures, including brain; gut; immune system; reproductive system; and white fat. Used to study benign neonatal seizures and developmental and epileptic encephalopathy 7. Human ortholog(s) of this gene implicated in benign neonatal seizures and developmental and epileptic encephalopathy 7. Orthologous to human KCNQ2 (potassium voltage-gated channel subfamily Q member 2). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Kcnq2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Kcnq2 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Kcnq2 gene, providing context for its role in the cell.