Cpm Gene Summary [Mouse]
Predicted to enable metallocarboxypeptidase activity. Predicted to be involved in peptide metabolic process and protein processing. Predicted to be located in plasma membrane and side of membrane. Predicted to be active in extracellular space. Is expressed in several structures, including alimentary system; embryo endoderm; genitourinary system; limb long bone; and sensory organ. Orthologous to human CPM (carboxypeptidase M). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Processed Transcript |
| Official Symbol | Cpm |
| Official Name | carboxypeptidase M [Source:MGI Symbol;Acc:MGI:1917824] |
| Ensembl ID | ENSMUSG00000020183 |
| Bio databases IDs | |
| Aliases | carboxypeptidase M |
| Synonyms | 1110060I01RIK, 5730456K23RIK, Carboxypeptidase M, E030045M14RIK |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cpm often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- carboxypeptidase M
- Zinc carboxypeptidase
- carboxypeptidase
- Zn_pept domain
- peptidase
- metallocarboxypeptidase
- Peptidase_M14NE-CP-C_like
- M14 family of metallocarboxypeptidases and related proteins
- Carboxypeptidase regulatory-like domain
Pathways
Biological processes and signaling networks where the Cpm gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- astigmatism
- proliferative diabetic retinopathy
- vertigo
role in cell
- production in
- binding in
- phosphorylation in
- osteogenesis by
- adipogenesis by
- signaling in
- turnover in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- detergent-soluble membrane fractions
- membrane fraction
- detergent resistant lipid raft fraction
- Extracellular Space
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cpm gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- peptide metabolic process
- anatomical structure morphogenesis
- protein processing
Cellular Component
Where in the cell the gene product is active
- extracellular space
- extracellular vesicular exosome
- extracellular region
- plasma membrane
- cell surface
Molecular Function
What the gene product does at the molecular level
- carboxypeptidase activity
- zinc ion binding
- metallocarboxypeptidase activity