Myl7 Gene Summary [Mouse]
Predicted to enable calcium ion binding activity. Predicted to be involved in cardiac muscle tissue development and heart contraction. Located in dendritic spine. Is expressed in several structures, including gastrocnemius muscle; heart; liver; uterus; and vascular system. Orthologous to human MYL7 (myosin light chain 7). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Myl7 |
| Official Name | myosin, light polypeptide 7, regulatory [Source:MGI Symbol;Acc:MGI:107495] |
| Ensembl ID | ENSMUSG00000020469 |
| Bio databases IDs | |
| Aliases | myosin, light polypeptide 7, regulatory |
| Synonyms | Mlc20, MLC2a, MLC-2alpha, MYL2A, MYLC2A, Myosin light chain 2a, myosin light chain 7, myosin, light polypeptide 7, regulatory, RLC-A |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Myl7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- EF-hand, calcium binding motif
- EF-hand domain
- EF-hand domain pair
- EF hand
- EFh
- enzyme
- protein binding
Pathways
Biological processes and signaling networks where the Myl7 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
- Actin Cytoskeleton Signaling
- Agranulocyte Adhesion and Diapedesis
- Apelin Cardiomyocyte Signaling Pathway
- Calcium Signaling
- Cardiac Hypertrophy Signaling
- Cdc42 Signaling
- Cellular Effects of Sildenafil (Viagra)
- CXCR4 Signaling
- Ephrin A Signaling
- Epithelial Adherens Junction Signaling
- Estrogen Receptor Signaling
- G-Protein Coupled Receptor Signaling
- Gα12/13 Signaling
- Hepatic Fibrosis / Hepatic Stellate Cell Activation
- IL-8 Signaling
- ILK Signaling
- Integrin Signaling
- PAK Signaling
- Regulation of Actin-based Motility by Rho
- RhoA Signaling
- RhoGDI Signaling
- Signaling by Rho Family GTPases
- Thrombin Signaling
- Tight Junction Signaling
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cell-cell contacts
- sarcomere
- cytosol
- dendritic spines
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Myl7 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- heart contraction
- cardiac muscle tissue development
Cellular Component
Where in the cell the gene product is active
- myosin complex
- cytoplasm
- dendritic spine
- cytosol
- A band
- myofibril
Molecular Function
What the gene product does at the molecular level
- protein binding
- calcium ion binding