Atp5c1 Gene Summary [Mouse]
Predicted to contribute to ATP hydrolysis activity and proton-transporting ATP synthase activity, rotational mechanism. Predicted to be involved in proton motive force-driven mitochondrial ATP synthesis. Located in mitochondrial inner membrane and myelin sheath. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human ATP5F1C (ATP synthase F1 subunit gamma). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Atp5c1 |
| Official Name | ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 [Source:MGI Symbol;Acc:MGI:1261437] |
| Ensembl ID | ENSMUSG00000025781 |
| Bio databases IDs | |
| Aliases | ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 |
| Synonyms | 1700094F02Rik, ATP5C, ATP5C1, ATP5CL1, ATPG, ATP synthase F1 subunit gamma, ATP synthase F1 subunit γ, F1 γ, γ subunit f1f0 atpase |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Atp5c1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- adenosine-tetraphosphatase
- ATP synthase
- enzyme
- protein binding
- hydrogen-transporting ATP synthase activity, rotational mechanism
- ATPase
- mitochondrial ATP synthase gamma subunit
Pathways
Biological processes and signaling networks where the Atp5c1 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- myelin enriched fraction
- pH resistant lipid raft fraction
- cristae-like membrane
- cellular membrane
- Plasma Membrane
- Mitochondria
- mitochondrial matrix
- mitochondrial inner membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Atp5c1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- oxidative phosphorylation
- ATP biosynthetic process
- ATP synthesis coupled proton transport
- mitochondrial ATP synthesis coupled proton transport
Cellular Component
Where in the cell the gene product is active
- mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)
- mitochondrial matrix
- mitochondrion
- membrane
- mitochondrial inner membrane
- mitochondrial proton-transporting ATP synthase complex
Molecular Function
What the gene product does at the molecular level
- ATPase activity
- RNA binding
- protein binding
- hydrogen ion transporting ATP synthase activity, rotational mechanism