Ptprn

Predicted to enable GTPase binding activity; spectrin binding activity; and ubiquitin-like protein ligase binding activity. Involved in insulin secretion involved in cellular response to glucose stimulus; luteinization; and positive regulation of type B pancreatic cell proliferation. Predicted to be located in several cellular components, including Golgi apparatus; axon terminus; and neuronal cell body. Predicted to be active in secretory granule and synapse. Is expressed in lens vesicle and nervous system. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human PTPRN (protein tyrosine phosphatase receptor type N). [provided by Alliance of Genome Resources, Apr 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ptprn often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Ptprn gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Ptprn gene, providing context for its role in the cell.