Csrp1 Gene Summary [Mouse]
Predicted to enable actinin binding activity. Predicted to be a structural constituent of muscle. Predicted to be involved in muscle tissue development and sarcomere organization. Predicted to act upstream of or within actin cytoskeleton organization. Predicted to be located in actin cytoskeleton and nucleoplasm. Predicted to be active in Z disc and nucleus. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and sensory organ. Orthologous to human CSRP1 (cysteine and glycine rich protein 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Csrp1 |
| Official Name | cysteine and glycine-rich protein 1 [Source:MGI Symbol;Acc:MGI:88549] |
| Ensembl ID | ENSMUSG00000026421 |
| Bio databases IDs | |
| Aliases | cysteine and glycine-rich protein 1 |
| Synonyms | CRP, CRP1, CSRP, CYRP, Cysteine and glycine rich protein 1, D1S181E, HEL-141, HEL-S-286 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Csrp1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- zinc ion binding
- LIM is a small protein-protein interaction domain, containing two zinc fingers
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- schizophrenia
- preeclampsia
- chronic sinusitis
- organismal death
- congenital heart disease
role in cell
- growth
- aggregation
- formation
- formation in
- growth in
- branching in
- organization
- branching
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- detergent resistant lipid raft fraction
- actin cytoskeleton
- nucleoplasm
- nucleoli
- filopodia
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Csrp1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- sarcomere organization
- muscle tissue development
- platelet aggregation
Cellular Component
Where in the cell the gene product is active
- Z disc
- nucleus
- extracellular vesicular exosome
- focal adhesion
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- zinc ion binding
- RNA binding
- structural constituent of muscle
- protein binding
- actinin binding