Ahctf1 Gene Summary [Mouse]
Predicted to enable DNA binding activity. Predicted to be involved in nuclear pore complex assembly and regulation of cytokinesis. Located in cytoplasm and nuclear matrix. Is expressed in several structures, including cardiovascular system; central nervous system; early conceptus; genitourinary system; and hemolymphoid system. Orthologous to human AHCTF1 (AT-hook containing transcription factor 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ahctf1 |
| Official Name | AT hook containing transcription factor 1 [Source:MGI Symbol;Acc:MGI:1915033] |
| Ensembl ID | ENSMUSG00000026491 |
| Bio databases IDs | |
| Aliases | AT hook containing transcription factor 1 |
| Synonyms | 6230412P20Rik, AT-hook containing transcription factor 1, ELYS, LOC100365024, MST108, MSTP108, RGD1561291, TMBS62 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ahctf1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- transcription regulator
- Nuclear pore complex assembly
- beta-propeller of ELYS nucleoporin
Pathways
Biological processes and signaling networks where the Ahctf1 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- infection by HIV-1
- alcoholism
- hyperzincemia and hypercalprotectinemia autoinflammatory syndrome
role in cell
- size
- hematopoiesis
- cytokinesis in
- assembly
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- cytosol
- nuclear pores
- nucleoplasm
- nuclear bodies
- nuclear envelope
- nuclear matrix
- kinetochores
- chromatin
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ahctf1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell division
- nucleocytoplasmic transport
- protein transport
- regulation of cytokinesis
- nuclear pore complex assembly
- mRNA transport
Cellular Component
Where in the cell the gene product is active
- Nup107-160 complex
- nuclear body
- kinetochore
- chromatin
- nucleoplasm
- nuclear pore
- nuclear envelope
- nucleus
- nuclear membrane
- extracellular vesicular exosome
- nuclear matrix
- cytosol
Molecular Function
What the gene product does at the molecular level
- DNA binding