Rcan2 Gene Summary [Mouse]
Predicted to enable calcium-dependent protein serine/threonine phosphatase regulator activity. Acts upstream of or within several processes, including calcineurin-NFAT signaling cascade; locomotion involved in locomotory behavior; and short-term memory. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; immune system; liver; retina; and stomach. Orthologous to human RCAN2 (regulator of calcineurin 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rcan2 |
| Official Name | regulator of calcineurin 2 [Source:MGI Symbol;Acc:MGI:1858219] |
| Ensembl ID | ENSMUSG00000039601 |
| Bio databases IDs | |
| Aliases | regulator of calcineurin 2 |
| Synonyms | CSP2, Dcip2, DSCR1-1L, DSCR1L1, MCIP2, RCN2, regulator of calcineurin 2, ZAKI-4 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rcan2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- RNA recognition motif (RRM) superfamily
- Calcipressin
Pathways
Biological processes and signaling networks where the Rcan2 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- schizophrenia
- androgenic alopecia
- plaque psoriasis
- Alzheimer disease
- neuroticism
- prostatic intraepithelial neoplasm
- prostatic intraepithelial neoplasia
- hyperactive behavior
- hemangioma
- angiomatosis
role in cell
- apoptosis
- migration
- proliferation
- abnormal morphology
- function
- tubulation
- dephosphorylation in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rcan2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- calcium-mediated signaling
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- nucleic acid binding
- calcium-dependent protein serine/threonine phosphatase regulator activity