CEP20 Gene Summary [Human]
Enables identical protein binding activity. Involved in cilium assembly. Located in centriolar satellite and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | CEP20 |
| Official Name | centrosomal protein 20 [Source:HGNC Symbol;Acc:HGNC:26435] |
| Ensembl ID | ENSG00000133393 |
| Bio databases IDs | |
| Aliases | centrosomal protein 20, pluripotent embryonic stem cell-related protein, FOP-related protein of 20 kDa |
| Synonyms | 0610037P05Rik, C16orf63, centrosomal protein 20, FOPNL, FOR20, PHSECRG2, RGD1305823 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CEP20 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- LisH
- identical protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- overall survival
- non-small cell lung cancer
regulated by
- CLOCK
- budesonide
role in cell
- expression in
- proliferation
- migration
- invasion by
- assembly
- polymerization
- polymerization in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- motile cilia
- basal bodies
- centrosome
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CEP20 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cilium morphogenesis
- microtubule anchoring
Cellular Component
Where in the cell the gene product is active
- motile cilium
- centrosome
- cilium basal body
- cytoplasm
- centriole
- centriolar satellite
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding