Ncapg Gene Summary [Mouse]
Predicted to be involved in mitotic chromosome condensation and positive regulation of chromosome condensation. Located in condensed chromosome, centromeric region and cytoplasm. Part of condensin complex. Is expressed in several structures, including lung; metanephros; nose; tooth; and ventricular layer. Orthologous to human NCAPG (non-SMC condensin I complex subunit G). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ncapg |
| Official Name | non-SMC condensin I complex, subunit G [Source:MGI Symbol;Acc:MGI:1930197] |
| Ensembl ID | ENSMUSG00000015880 |
| Bio databases IDs | |
| Aliases | non-SMC condensin I complex, subunit G |
| Synonyms | 5730507H05Rik, CAPG, CHCG, HCAP-G, MFT.M05.13, non-SMC condensin I complex subunit G, non-SMC condensin I complex, subunit G, NY-MEL-3, RGD1562646, YCG1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ncapg often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Nuclear condensing complex subunits, C-term domain
- protein binding
- HEAT repeats
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- non-small cell lung carcinoma
- neoplasia
- tumorigenesis
- hepatocellular carcinoma
- liver cancer
- epithelial cancer
- B cell cancer
- cancer
- epithelial neoplasia
- metastasis
role in cell
- expression in
- migration
- proliferation
- apoptosis
- growth
- production in
- quantity
- phosphorylation in
- invasion by
- activity
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- chromatin fraction
- Cytoplasm
- cytosol
- chromosome
- germinal vesicles
- centromeres
- chromosomal arms
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ncapg gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell division
- positive regulation of chromosome segregation
- mitotic chromosome condensation
Cellular Component
Where in the cell the gene product is active
- condensed chromosome
- nucleus
- cytoplasm
- membrane
- condensed chromosome, centromeric region
- cytosol
- condensin complex
- condensed nuclear chromosome
Molecular Function
What the gene product does at the molecular level
- protein binding