Il17ra

Enables interleukin-17 receptor activity and signaling receptor binding activity. Involved in several processes, including T-helper 17 type immune response; interleukin-17-mediated signaling pathway; and positive regulation of cytokine production involved in inflammatory response. Acts upstream of or within positive regulation of interleukin-13 production and positive regulation of interleukin-5 production. Located in plasma membrane. Is expressed in heart and thymus primordium. Human ortholog(s) of this gene implicated in immunodeficiency 51. Orthologous to human IL17RA (interleukin 17 receptor A). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Il17ra often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Il17ra gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Il17ra gene, providing context for its role in the cell.