Itgb8

Predicted to enable extracellular matrix protein binding activity and integrin binding activity. Acts upstream of or within several processes, including hard palate development; mononuclear cell differentiation; and transforming growth factor beta receptor signaling pathway. Part of integrin alphav-beta8 complex. Is expressed in several structures, including alimentary system; male reproductive system; nervous system; sensory organ; and skeleton. Orthologous to human ITGB8 (integrin subunit beta 8). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Itgb8 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Itgb8 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Itgb8 gene, providing context for its role in the cell.