Wnt10a

Predicted to enable cytokine activity and frizzled binding activity. Predicted to be involved in several processes, including cellular response to transforming growth factor beta stimulus; hair follicle morphogenesis; and tongue development. Predicted to act upstream of or within neural crest cell differentiation; positive regulation of gene expression; and regulation of odontogenesis of dentin-containing tooth. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in Schopf-Schulz-Passarge syndrome; ectodermal dysplasia; and tooth agenesis. Orthologous to human WNT10A (Wnt family member 10A). [provided by Alliance of Genome Resources, Apr 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Wnt10a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Wnt10a gene in rat plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the rat Wnt10a gene, providing context for its role in the cell.