Il1rap

Enables interleukin-1 receptor activity and interleukin-33 receptor activity. Involved in several processes, including interleukin-33-mediated signaling pathway; positive regulation of cytokine production; and regulation of synapse assembly. Acts upstream of or within cytokine-mediated signaling pathway. Is active in glutamatergic synapse. Is expressed in several structures, including aorta-gonad-mesonephros; brain ventricle and choroid plexus; forebrain; renal calyx; and ventral grey horn. Orthologous to human IL1RAP (interleukin 1 receptor accessory protein). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Il1rap often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Il1rap gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Il1rap gene, providing context for its role in the cell.