Adcy8

Enables several functions, including calcium- and calmodulin-responsive adenylate cyclase activity; calmodulin binding activity; and protein dimerization activity. Involved in several processes, including G protein-coupled receptor signaling pathway; activation of protein kinase A activity; and cAMP biosynthetic process. Located in several cellular components, including caveola; clathrin-coated pit; and neuronal cell body membrane. Orthologous to human ADCY8 (adenylate cyclase 8). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Adcy8 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Adcy8 gene in rat plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the rat Adcy8 gene, providing context for its role in the cell.