Gnat1

Enables GTP binding activity. Involved in several processes, including G protein-coupled opsin signaling pathway; detection of chemical stimulus involved in sensory perception of bitter taste; and positive regulation of cyclic-nucleotide phosphodiesterase activity. Located in several cellular components, including apical plasma membrane; photoreceptor inner segment; and photoreceptor outer segment. Part of heterotrimeric G-protein complex. Human ortholog(s) of this gene implicated in congenital stationary night blindness 1G; congenital stationary night blindness autosomal dominant 3; and night blindness. Orthologous to human GNAT1 (G protein subunit alpha transducin 1). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Gnat1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Gnat1 gene in rat plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the rat Gnat1 gene, providing context for its role in the cell.