Details

Type
Protein Coding
Official Symbol
C4b
Official Name
complement C4B (Chido blood group) [Source:RGD Symbol;Acc:1591983]
Ensembl ID
ENSRNOG00000030729
Bio databases IDs NCBI: 406161 Ensembl: ENSRNOG00000030729
Aliases complement C4B (Chido blood group)
Synonyms C4, C4-1, C4-2, C4a, C4b, C4l, complement C4A, complement C4A (Rodgers blood group), complement C4B, complement C4B (Chido blood group), LOC100909666, LOC102549354, LOC103689965, Slp, SlpA, Slp-w7, Ss
Species
Rat, Rattus norvegicus
OrthologiesMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat C4b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • NTR_like
  • Alpha-2-macroglobulin bait region domain
  • ISOPREN_C2_like
  • binding protein
  • A-macroglobulin TED domain
  • A-macroglobulin receptor binding domain
  • protein binding
  • carbohydrate binding
  • ANATO
  • Alpha-2-macroglobulin family
  • Macroglobulin domain MG3
  • MG2 domain

Pathways

Biological processes and signaling networks where the C4b gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • lymphadenopathy
  • polycystic kidney disease
  • purkinje cell degeneration
  • splenomegaly
  • rheumatoid arthritis
  • Alzheimer disease
  • bullous pemphigoid
  • glomerulonephritis
  • peritonitis
  • cerebral malaria
regulated by
regulates
role in cell
  • number
  • activation
  • apoptosis
  • quantity
  • innate immune response
  • density
  • cellular infiltration by
  • accumulation
  • engulfment
  • degranulation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • synapse
  • perikaryon
  • axons
  • dendrites

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.