Gnb5

Enables GTPase activating protein binding activity. Predicted to be involved in G protein-coupled dopamine receptor signaling pathway; negative regulation of voltage-gated calcium channel activity; and positive regulation of GTPase activity. Predicted to act upstream of or within G protein-coupled receptor signaling pathway; dark adaptation; and light adaption. Located in cell body. Part of protein-containing complex. Human ortholog(s) of this gene implicated in intellectual developmental disorder with cardiac arrhythmia. Orthologous to human GNB5 (G protein subunit beta 5). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Gnb5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Gnb5 gene in rat plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the rat Gnb5 gene, providing context for its role in the cell.