Fzd7

Enables Wnt receptor activity and Wnt-protein binding activity. Involved in negative regulation of cell-substrate adhesion. Acts upstream of or within several processes, including Wnt signaling pathway; skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration; and substrate adhesion-dependent cell spreading. Located in plasma membrane. Is expressed in several structures, including alimentary system; brain; embryo mesenchyme; genitourinary system; and sensory organ. Orthologous to human FZD7 (frizzled class receptor 7). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Fzd7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Fzd7 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Fzd7 gene, providing context for its role in the cell.