Gng13 Gene Summary [Mouse]
Predicted to enable G-protein beta-subunit binding activity. Acts upstream of or within phospholipase C-activating G protein-coupled receptor signaling pathway and sensory perception of taste. Located in dendrite. Part of heterotrimeric G-protein complex. Is active in synapse. Is expressed in brain; gonad; gut; and liver. Orthologous to human GNG13 (G protein subunit gamma 13). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Gng13 |
| Official Name | guanine nucleotide binding protein (G protein), gamma 13 [Source:MGI Symbol;Acc:MGI:1925616] |
| Ensembl ID | ENSMUSG00000025739 |
| Bio databases IDs | |
| Aliases | guanine nucleotide binding protein (G protein), gamma 13 |
| Synonyms | 1500031D04Rik, Ggamma13, G(gamma)13, G protein subunit gamma 13, G protein subunit γ 13, guanine nucleotide binding protein (G protein), gamma 13, guanine nucleotide binding protein (G protein), γ 13, Gγ13, G(γ)13, h2-35, HG3J, LOC682159 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gng13 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- GGL
- enzyme
- protein binding
- GGL domain
Pathways
Biological processes and signaling networks where the Gng13 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
- AMPK Signaling
- Androgen Signaling
- Antiproliferative Role of Somatostatin Receptor 2
- Apelin Endothelial Signaling Pathway
- Apelin Muscle Signaling Pathway
- Cardiac β-adrenergic Signaling
- CCR3 Signaling in Eosinophils
- CCR5 Signaling in Macrophages
- CXCR4 Signaling
- Endocannabinoid Developing Neuron Pathway
- Ephrin B Signaling
- Ephrin Receptor Signaling
- fMLP Signaling in Neutrophils
- G Beta Gamma Signaling
- Glutamate Receptor Signaling
- Gustation Pathway
- Gαq Signaling
- IL-1 Signaling
- IL-8 Signaling
- Molecular Mechanisms of Cancer
- P2Y Purinergic Receptor Signaling Pathway
- Protein Kinase A Signaling
- Relaxin Signaling
- RhoGDI Signaling
- Thrombin Signaling
- α-Adrenergic Signaling
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- Cytoplasm
- cellular membrane
- olfactory cilia
- synapse
- dendrites
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Gng13 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- sensory perception of taste
- G-protein coupled receptor signaling pathway
- phospholipase C-activating G-protein coupled receptor signaling pathway
Cellular Component
Where in the cell the gene product is active
- dendrite
- heterotrimeric G-protein complex
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- G-protein beta-subunit binding