Pdgfc

Enables platelet-derived growth factor receptor binding activity. Involved in positive regulation of cold-induced thermogenesis. Acts upstream of or within several processes, including platelet-derived growth factor receptor signaling pathway; positive regulation of fibroblast proliferation; and regulation of protein phosphorylation. Located in extracellular region. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and sensory organ. Orthologous to human PDGFC (platelet derived growth factor C). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Pdgfc often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Pdgfc gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Pdgfc gene, providing context for its role in the cell.