Pdgfc

Predicted to enable platelet-derived growth factor receptor binding activity and protein homodimerization activity. Predicted to be involved in several processes, including platelet-derived growth factor receptor signaling pathway; positive regulation of cold-induced thermogenesis; and positive regulation of intracellular signal transduction. Predicted to act upstream of or within several processes, including cellular response to amino acid stimulus; positive regulation of fibroblast proliferation; and regulation of protein phosphorylation. Predicted to be located in several cellular components, including cell surface; cytosol; and extracellular region. Predicted to be active in extracellular space. Orthologous to human PDGFC (platelet derived growth factor C). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Pdgfc often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Pdgfc gene in rat plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the rat Pdgfc gene, providing context for its role in the cell.