Target List
Cell Adhesion Molecules
Cell-Cell Adhesion​
Cdh1 (E-cadherin), Cdh11, Cdh6, Cdh8, Fat1, Nf2
Transmembrane Receptors​
Cd44, Itga7, Itgb3
Other Cell Adhesion Molecules​
Apc, Fn1, Sdc4, Mtss1
Extracellular Matrix (ECM) Molecules
Extracellular Matrix (ECM) Proteases​
Mmp10, Mmp11, Mmp13, Mmp2, Mmp3, Mmp7, Mmp9
Extracellular Matrix (ECM) Protease Inhibitors​
Timp2, Timp3, Timp4
Other Extracellular Matrix (ECM) Molecules​
Col4a2
Cell Cycle
Regulation of the Cell Cycle​
Hras, Il1b, Kras, Tgfb1, Vegfa
Negative Regulation of the Cell Cycle​
Apc, Brms1, Cdkn2a (INK4A, p16, p19ARF), Nf2, Pten, Rb1, Tp53 (p53)
Cell Cycle Arrest & Checkpoints​
Mdm2
Cell Growth & Proliferation
Regulation of Cell Proliferation​
Gnrh1, Kiss1r, Il18, Kiss1, Myc, Nf2, Tgfb1, Tp53 (p53)
Growth Factors & Hormones​
Csf1 (Mcsf), Gnrh1, Hgf, Igf1, Tgfb1, Vegfa
Cytokines & Chemokines​
Ccl7 (Mcp-3), Cxcl12, Il18, Il1b, Tnfsf10 (Trail)
Cell Surface Receptors​
Cxcr4, Ephb2, Fgfr4, Flt4 (Vegfr2), Kiss1r, Cxcr2, Met, Nr4a3 (Nor1), Plaur (uPAR), Rorb, Sstr2, Tshr
Other Cell Growth Genes​
Brms1, LOC689601, Hras, Kras, Mycl, Mdm2, Src, Trpm1
Apoptosis
Induction of Apoptosis​
Il18, Myc, Pten
Other Apoptosis Genes​
Tnfsf10 (Trail), Tp53 (p53)
Transcription Factors & Regulators
Transcription Factors​
Cdkn2a (INK4A, p16, p19ARF), Etv4, Mycl, Mta1, Myc, Nr4a3 (Nor1), Rorb, Smad4, Tcf20, Tp53 (p53)
Transcriptional Regulation​
Chd4, Ewsr1, Rb1, Smad2
Other Tumor Metastasis Genes
Cst7, Ctbp1, Ctsk, Ctsl, Elane, Fxyd5, Hnrnpab, Hpse, Htatip2, Cd82, Mcam, Nme1 (Nm23a), Nme2, Nme4, Pnn, Syk