Target List
Autophagy Machinery Components
Autophagic Vacuole Formation
Ambra1, Atg12, Atg16l1, Atg4b, Atg4c, Atg5, Atg9a, Becn1, Ctsd, Gabarap, Gabarapl2, Irgm, Map1lc3a, Map1lc3b, Psen1, Rb1cc1, Atg101, Rgs19, Tm9sf1, Ulk1, Wipi1
Vacuole Targeting
Atg4b, Atg4c, Gabarap
Protein Transport
Atg16l1, Atg16l2, Atg3, Atg4b, Atg4c, Atg7, Atg9a, Gabarap, Gabarapl2, Rab24
Ubiquitination
Atg3, Atg7, Park2 (QuantiNova Symbol: AABR07001519.1), Park7, Pink1
Proteases
Atg4b, Atg4c
Regulation of Autophagy
Co-Regulators of Autophagy & Apoptosis
Akt1, App, Atg12, Atg5, Bad, Bak1, Bax, Bcl2, Bcl2l1 (Bcl-xl), Bcl2l1 (Bcl-xl), Bcl2l1 (Bcl-xl), Becn1, Bid, Bnip3, Casp3, Casp8 (Flice), Npc1, Cdkn1b (P27KIP1), Cdkn2a (INK4A, p16, p19ARF), Cln3, Ctsb, Cxcr4, Dapk1, Eif2ak3, Fadd, Fas, Hdac1, Htt, Ifng, Igf1, Ins2, Mapk8 (Jnk1), Mtor, Nfkb1, Park2 (QuantiNova Symbol: AABR07001519.1), Pik3cg, Prkaa1 (Ampk), Pten, Snca, Sqstm1, Tgfb1, Tgm2, Tnf, Tnfsf10 (Trail), Tp53 (p53)
Co-Regulators of Autophagy & the Cell Cycle
Bax, Cdkn1b (P27KIP1), Cdkn2a (INK4A, p16, p19ARF), Ifng, Mapt, Pim2, Pten, Rb1, Tgfb1, Tp53 (p53)
Autophagy Induction by Intracellular Pathogens
Eif2ak3, Ifng, Lamp1
Autophagy in Response to Other Intracellular Signals
Arsa, Ctss, Dram2, Eif4g1, Esr1 (Erα), Gaa, Hdac6, Hgs, Mapk14 (p38alpha), Pik3c3 (Vps34), Pik3r4, Rps6kb1
Chaperone-Mediated Autophagy
Hsp90aa1