dPCR LNA Mutation Assays

For detecting specific DNA sequence mutations related to cancer and oncogenesis

  • Duplex assay design detects mutated and wild-type sequences
  • Choice of FAM + HEX or Atto 550 + ROX fluorescent dye combinations
  • LNA-enhanced primers and probes increase assay specificity and sensitivity
  • Wet-lab tested dPCR assays available for more than 200 targets
  • Suitable for use with circulating tumor DNA, liquid biopsy, FFPE and other tissue samples
  • Intended for use with QIAcuity Probe PCR Kits

Product

Product List41 products

Verification
dPCR wet-lab validated (39)
dPCR wet-lab verified (2)
GeneGlobe ID: DMH0000246 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay EGFR 12384 Human
AA Mutation: p.E746_S752delinsV
Nucleotide Mutation: c.2237_2255delinsT
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000248 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay EGFR 12378 Human
AA Mutation: p.D770_N771insG
Nucleotide Mutation: c.2310_2311insGGT
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000386 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay EGFR 6224 Human
AA Mutation: p.L858R
Nucleotide Mutation: c.2573T>G
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000076 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay EGFR 6255 Human
AA Mutation: p.L747_S752del
Nucleotide Mutation: c.2239_2256del
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000041 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay EGFR 12988 Human
AA Mutation: p.E709K
Nucleotide Mutation: c.2125G>A
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0001098 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay EGFR 4170221 Human
AA Mutation: p.L747_A750delinsS
Nucleotide Mutation: c.2240_2248del
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0001097 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay EGFR 6210 Human
AA Mutation: p.L747_T751delinsS
Nucleotide Mutation: c.2240_2251del
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000260 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay EGFR 13551 Human
AA Mutation: p.E746_T751delinsI
Nucleotide Mutation: c.2235_2252delinsAAT
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000305 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay EGFR 12386 Human
AA Mutation: p.E746_T751delinsV
Nucleotide Mutation: c.2237_2252delinsT
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000073 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay EGFR 12383 Human
AA Mutation: p.L747_T751delinsP
Nucleotide Mutation: c.2239_2251delinsC
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000308 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay EGFR 6241 Human
AA Mutation: p.S768I
Nucleotide Mutation: c.2303G>T
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000254 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay EGFR 12422 Human
AA Mutation: p.L747_A750delinsP
Nucleotide Mutation: c.2238_2248delinsGC
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000280 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay EGFR 6253 Human
AA Mutation: p.G719C
Nucleotide Mutation: c.2155G>T
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000079 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay EGFR 13552 Human
AA Mutation: p.E746_T751delinsIP
Nucleotide Mutation: c.2235_2251delinsAATTC
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000085 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay EGFR 6240 Human
AA Mutation: p.T790M
Nucleotide Mutation: c.2369C>T
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000397 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay EGFR 12371 Human
AA Mutation: p.E709V
Nucleotide Mutation: c.2126A>T
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000258 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay EGFR 12678 Human
AA Mutation: p.E746_T751delinsA
Nucleotide Mutation: c.2237_2251del
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000269 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay EGFR 12387 Human
AA Mutation: p.L747_P753delinsQ
Nucleotide Mutation: c.2239_2258delinsCA
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000232 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay EGFR 6220 Human
AA Mutation: p.E746_S752delinsD
Nucleotide Mutation: c.2238_2255del
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000276 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay EGFR 6223 Human
AA Mutation: p.E746_A750del
Nucleotide Mutation: c.2235_2249del
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000055 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay EGFR 6252 Human
AA Mutation: p.G719S
Nucleotide Mutation: c.2155G>A
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000082 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay EGFR 26038 Human
AA Mutation: p.K745_E749del
Nucleotide Mutation: c.2233_2247del
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000236 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay EGFR 12416 Human
AA Mutation: p.E746_T751delinsVA
Nucleotide Mutation: c.2237_2253delinsTTGCT
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000275 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay EGFR 12369 Human
AA Mutation: p.L747_T751del
Nucleotide Mutation: c.2240_2254del
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000070 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay EGFR 13550 Human
AA Mutation: p.E746_A750delinsIP
Nucleotide Mutation: c.2235_2248delinsAATTC
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000006 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay EGFR 6213 Human
AA Mutation: p.L861Q
Nucleotide Mutation: c.2582T>A
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000250 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay EGFR 12728 Human
AA Mutation: p.E746_T751del
Nucleotide Mutation: c.2236_2253del
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000274 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay EGFR 18427 Human
AA Mutation: p.E746_P753delinsVS
Nucleotide Mutation: c.2237_2257delinsTCT
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000007 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay EGFR 6493937 Human
AA Mutation: p.C797S
Nucleotide Mutation: c.2389T>A
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000072 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay EGFR 12367 Human
AA Mutation: p.E746_S752delinsA
Nucleotide Mutation: c.2237_2254del
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000252 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay EGFR 12403 Human
AA Mutation: p.L747_S752delinsQ
Nucleotide Mutation: c.2239_2256delinsCAA
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000262 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay EGFR 144206 Human
AA Mutation: p.L747_E749del
Nucleotide Mutation: c.2239_2247del
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000075 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay EGFR 12419 Human
AA Mutation: p.L747_T751delinsQ
Nucleotide Mutation: c.2238_2252delinsGCA
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000078 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay EGFR 13556 Human
AA Mutation: p.S752_I759del
Nucleotide Mutation: c.2253_2276del
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000240 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay EGFR 6225 Human
AA Mutation: p.E746_A750del
Nucleotide Mutation: c.2236_2250del
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000266 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay EGFR 12370 Human
AA Mutation: p.L747_P753delinsS
Nucleotide Mutation: c.2240_2257del
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000271 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay EGFR 13427 Human
AA Mutation: p.E709A
Nucleotide Mutation: c.2126A>C
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000304 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay EGFR 12382 Human
AA Mutation: p.L747_A750delinsP
Nucleotide Mutation: c.2239_2248delinsC
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000052 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay EGFR 5945664 Human
AA Mutation: p.C797S
Nucleotide Mutation: c.2390G>C
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000057 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay EGFR 6239 Human
AA Mutation: p.G719A
Nucleotide Mutation: c.2156G>C
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000273 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay EGFR 13558 Human
AA Mutation: p.A767_V769dup
Nucleotide Mutation: c.2309_2310delinsCCAGCGTGGAT
dPCR wet-lab validated
Product Specification
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Resources

Instrument User Manuals (1)
Quick-Start Protocols (1)
Safety Data Sheets (1)
Application Notes (1)
Digital PCR (dPCR) is a powerful technique that detects and quantifies ultra-rare mutations in a high background of wild-type cfDNA down to 0.1% variant allele frequency. Here, we describe end-to-end manual and automated workflows that enable accurate detection and absolute quantification of ultra-rare PIK3CA variants in cfDNA using the QIAcuity Digital PCR System.
Certificates of Analysis (1)